QS-21 injectable has been used in SHINGRIX, Mosquirix, Arexvy and other commercially available vaccines developed by GSK.QS-21 is an immunostimulatory saponin used as a potent vaccine adjuvant. It stimulates Th2 humoral immunity and Th1 cell-mediated immune responses by acting on antigen-presenting cells (APCs) and T cells. QS-21 activates the NLRP3 inflammasome, triggering the release of caspase-1-dependent cytokines IL-1β and IL-18, thereby enhancing antigen-specific immune responses.
Transport: At 2-8°C. Long-term storage: Sealed, protected from light at 2-8°C. Avoid: Exposure to strongly oxidizing agents. Retesting: Annual requalification required.
NMPA CDE registration no.: F20250000075
USFDA DMF no.: 041805
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